By A. Gunock. Schreiner College. 2017.

In this buy cheap minocin 100 mg on line, the journal you choose will need to be well suited to your research findings buy minocin 100 mg with visa, and the topic of your paper will need to fall within the scope of the journal. For example, the results of a large randomised controlled trial of an innovative and effective treatment for breast cancer may be best submitted to the New England Journal of Medicine. However, details of a newly identified gene may be best submitted to Nature Genetics, and an epidemiological study to assess the prevalence of a childhood illness may be best submitted to the Archives of Diseases in Childhood. The concept that negative results are harder to place than positive results is supported by documented publication bias. Classic examples of this are the delayed publication of negative results from randomised controlled trials16 and for studies that have reported non-significant health effects of passive smoking. However, regardless of the journal, your writing must always be easy to understand by both the external reviewers and the audience that you expect to reach. If your message is important, then delivering it in an entirely effective way will help to disseminate your results to the research and medical community where they really matter. On the other hand, if you don’t have an important question, good data with which to answer it, and a clear message for your audience, you should think twice about starting to write the paper. You should try to reach a consensus with your coauthors about preferred journals when you are first ready to start writing your paper. This will help you to decide on the style and the format in which you will write and, in turn, save you from the frustration and time that it takes to change your paper and the format of your citations from one journal to another. Since different journals require you to present your text and/or analyses in different formats, the earlier you make the decision about the journal the sooner you can begin formatting your paper in the correct style. Some journals resist figures and prefer tables, some journals resist the use of percentages and prefer you to give both the numerators and denominators in the tables, and some journals have a limit on the number of tables, figures, or citations that they will accept.

We ourselves have designed a technique in which positive correlation with progression purchase 50mg minocin free shipping. The bar chart in dots of light are projected onto the surface of the back and ⊡ Fig safe 50mg minocin. We used In a recent study the progression velocity of scolio- this method for 15 years. A grid pattern notable with a growth velocity of >or=2 cm/year, at ages is projected onto the surface of the back and a virtual between 9 and 13 years, bone ages between 9 and 14 »plaster cast« calculated. In boys, scolioses appear to progress at a later lordoses can be evaluated very reliably by computer and stage than in girls, even taking into account the skeletal any subsequent changes over time documented. If a scoliosis of >20° persists be- yond infancy, progression is inevitable. Additional imaging methods Computer tomography Progression in adulthood CT is suitable for checking rotation and has been used in In scolioses with a Cobb angle of over 50° on completion a number of clinical studies. Consequences of scoliosis Thanks to investigations involving substantial numbers Magnetic resonance imaging (MRI) of patients and observation periods of up to 50 years we MRI is a non-invasive, but expensive, method that can now know a great deal about the consequences of sco- be used for identifying intraspinal problems (anoma- lioses [3, 102, 103]. MRI is indicated if neurological symp- untreated scolioses is moderate after 50 years. It is not the incidence of back pain is increased, this is rarely seri- suitable for monitoring the progress of a condition as ous [103]. In the lumbar area, the outwardly visible cosmetic impairment only starts to appear from a lumbar prominence angle of 15° (corresponding to a Cobb angle of approx. Asymmetry of the waist, how- ever, can have a more detrimental effect on the cosmetic 3 appearance. Risk of progression in relation to age and the initial angle The probability of back pain is increased in: of the scoliosis. The probability of back pain is only slightly or moderately increased in patients with thoracic scolioses [3, 103]. Paralysis Spontaneously occurring paralysis does not occur in id- iopathic scoliosis (paralysis only occurs in cases of con- genital kyphosis and secondary scoliosis resulting from a tumor).

The central metacarpals are missing buy minocin 100mg amex, as are normally the middle finger minocin 50 mg sale, occa- sionally the index finger and rarely the ring finger. The second atypical form is a symbrachydactyly (of the split a b hand type), which is unilateral and not genetic in origin. Operations for radial clubhand: a Centralization, b The metacarpus is present, although several central fin- Radialization of the carpus. In the typical form the radial side tends to tendons, nerves and blood vessels will also be involved. The treatment is based on the functional im- occurs in association with a ring constriction syndrome. If syndactyly is present, deepening of the web Syndactylies can also form part of the Poland syndrome 3 space is indicated. While it may be examination, in addition to the skin union, we note the possible to lengthen rudimentary finger structures in the mobility of the joints and the length of the bones. Bone central part of the hand, few therapeutic procedures are shortening is not infrequently seen in cases of brachysyn- required in most cases, since relatively little functional dactyly, in which case the x-ray will also reveal any bony impairment is present. Since the »lob- ster-claw hand« is very unsightly, the request for recon- Treatment structive procedures is understandable. A narrowing Very early separation of the fusion is required in cases and amelioration of the cleft formation can be helpful of acrosyndactyly if the soft tissue connection produces in this respect. Early separation is also indicated if the connected Proximal humeral focal deficiency fingers are unequal in length. This also applies if a bony By analogy with a proximal femoral deficiency ( Chap- union is present. Bilateral humerus although, to our knowledge, this has not been syndactylies can be operated on during the same session.

This will ensure that everyone spends their time efficiently because the number of drafts is minimised and the quality of the feedback is maximised generic 100mg minocin with visa. By incorporating each reviewer’s improvements before you pass the document on again discount minocin 50mg free shipping, the next reviewer receives the most advanced version of your work and coauthors do not have to duplicate each other’s work. Some groups of coauthors find it is very productive to hold miniwriters’ groups and brainstorm some ideas together rather than reviewing in isolation. It is important to find a reviewing process that is both efficient and suits the work practices of your authorship team. As well as taking the coauthors’ and reviewers’ comments on board, you need to continually work on each paragraph so that the topic sentence is accurate and correct, the grammar is flawless, and the sentences have a minimum number of words and flow together nicely. This should not be an arduous task but rather a rewarding process of finding better ways to package your science, your results, and your ideas. Your paper is ready to circulate only when it gives you pleasure to read. It is up to you as the first author to decide whether you want verbal, written, or electronic feedback. Written feedback on a paper copy of your draft article is often the optimal way to proceed but this assumes that your reviewer’s handwriting is legible! There is an increased move towards electronic feedback using the “track changes” facilities of word processing packages. The problem is that if you send reviewers an electronic copy of your paper to edit on their screen, then you are in effect giving them temporary ownership of the document. Also, it can be difficult to transfer electronic changes to your master document if it has been altered since you gave a copy of it out for review.